Peptide-Driven Proton Sponge Nano-Assembly for Imaging and Triggering Lysosome-Regulated Immunogenic Cancer Cell Death.

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第一作者： Tengyu,He

第一单位： Program in Materials Science and Engineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.

作者： Tengyu,He ^[1] ; Jing,Wen ^[2] ; Wenjian,Wang ^[3] ; Zeliang,Hu ^[4] ; Chuxuan,Ling ^[5] ; Zhongchao,Zhao ^[5] ; Yong,Cheng ^[5] ; Yu-Ci,Chang ^[1] ; Ming,Xu ^[5] ; Zhicheng,Jin ^[5] ; Lubna,Amer ^[1] ; Lekshmi,Sasi ^[5] ; Lei,Fu ^[5] ; Nicole F,Steinmetz ^[6] ; Tariq M,Rana ^[2] ; Peng,Wu ^[3] ; Jesse V,Jokerst ^[7]

作者单位： Program in Materials Science and Engineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. ^[1] Division of Genetics, Program in Immunology, Bioinformatics and Systems Biology Program, Institute for Genomic Medicine, Department of Pediatrics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. ^[2] Department of Molecular & Cellular Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA. ^[3] Department of Chemistry and Biochemistry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. ^[4] Department of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. ^[5] Department of NanoEngineering, Department of Bioengineering, Department of Radiology, Center for Nano-ImmunoEngineering, Institute for Materials Discovery and Design, Moores Cancer Center, Center for Engineering in Cancer, Institute of Engineering in Medicine, Shu and K. C. Chien and Peter Farrell Collaboratory, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. ^[6] Program in Materials Science and Engineering, and Department of Radiology, Department of NanoEngineering, University of California San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. ^[7]

关键词 immunogenic cell death immunotherapies necroptosis peptides pyroptosis regulated necrosis self‐assembly