ILKAP Promotes the Metastasis of Hepatocellular Carcinoma Cells by Inhibiting β-Catenin Degradation and Enhancing the WNT Signaling Pathway.

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作者： Rui,Zhang ^[1] ; Jinglei,Yuan ^[1] ; Shicheng,Liu ^[1] ; Vincenzo,Torraca ^[2] ; Zhiquan,Liao ^[3] ; Yueyan,Wu ^[1] ; Hongfei,Tan ^[1] ; Xia,Yao ^[1] ; Xueyang,Hou ^[1] ; Hao,Lyu ^[1] ; Shuai,Xiao ^[1] ; Dong,Guo ^[1] ; Declan William,Ali ^[1] ; Marek,Michalak ^[4] ; Xing-Zhen,Chen ^[4] ; Cefan,Zhou ^[5] ; Jingfeng,Tang ^[1]

作者单位： National "111" Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, 430068, China. ^[1] School of Immunology & Microbial Sciences, Department of Infectious Diseases, King's College London, London, WC2R 2LS, UK. ^[2] School of Life Sciences, University of Westminster, London, W1B 2HW, UK. ^[3] Department of Biochemistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada. ^[4] Membrane Protein Disease Research Group, Department of Physiology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada. ^[5]

关键词 HCC ILKAP WNT pathway metastasis β‐catenin

主题词动物(Animals);人类(Humans);β连环素(beta Catenin);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);肝肿瘤(Liver Neoplasms);肿瘤转移(Neoplasm Metastasis);斑马鱼(Zebrafish);磷蛋白磷酸酶类(Phosphoprotein Phosphatases)

DOI 10.1002/adbi.202300117

PMID 38379270

发布时间 2024-06-26

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Advanced biology

2024年8卷5期

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ILKAP Promotes the Metastasis of Hepatocellular Carcinoma Cells by Inhibiting β-Catenin Degradation and Enhancing the WNT Signaling Pathway.

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ILKAP Promotes the Metastasis of Hepatocellular Carcinoma Cells by Inhibiting β-Catenin Degradation and Enhancing the WNT Signaling Pathway.

Advanced biology

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Advanced biology

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