换一批A tumor suppressor protein encoded by circKEAP1 inhibits osteosarcoma cell stemness and metastasis by promoting vimentin proteasome degradation and activating anti-tumor immunity.
第一作者：
Ying,Zhang
第一单位：
Department of Radiotherapy, Cancer Hospital of Shantou University Medical College, No. 7 Raoping Road, Shantou, Guangdong, 515041, PR China. yzhangmimazi@stu.edu.cn.;Sports Medicine Center, First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China. yzhangmimazi@stu.edu.cn.
作者：
主题词
人类(Humans);骨肿瘤(Bone Neoplasms);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);微RNAs(MicroRNAs);NF-E2相关因子2(NF-E2-Related Factor 2);骨肉瘤(Osteosarcoma);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);肿瘤抑制蛋白质类(Tumor Suppressor Proteins);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);波形蛋白(Vimentin)
DOI
10.1186/s13046-024-02971-7
PMID
38383479
发布时间
2024-03-13
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