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An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer.

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第一作者： Nishat,Manzar

第一单位： Molecular Oncology Laboratory, Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, UP 208016, India.

作者： Nishat,Manzar ^[1] ; Umar Khalid,Khan ^[1] ; Ayush,Goel ^[1] ; Shannon,Carskadon ^[2] ; Nilesh,Gupta ^[3] ; Nallasivam,Palanisamy ^[2] ; Bushra,Ateeq ^[4]

作者单位： Molecular Oncology Laboratory, Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, UP 208016, India. ^[1] Vattikuti Urology Institute, Department of Urology, Henry Ford Health System, Detroit, MI 48202, USA. ^[2] Department of Pathology, Henry Ford Health System, Detroit, MI 48202, USA. ^[3] Molecular Oncology Laboratory, Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, UP 208016, India.;Mehta Family Center for Engineering in Medicine, Indian Institute of Technology Kanpur, Kanpur, UP 208016, India.;Centre of Excellence for Cancer - Gangwal School of Medical Sciences and Technology, Indian Institute of Technology Kanpur, Kanpur, UP 208016, India. ^[4]

关键词 Cancer Proteomics

DOI 10.1016/j.isci.2024.108794

PMID 38384854

发布时间 2026-02-04

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An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer.

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An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer.

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