Alpha-fetoprotein upregulates hepatocellular carcinoma cell-intrinsic PD-1 expression through the LATS2/YAP/TEAD1 pathway.

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作者： Guangxian,Leng ^[1] ; Hongxia,Gong ^[2] ; Guiyuan,Liu ^[3] ; Yin,Kong ^[4] ; Liuqing,Guo ^[1] ; Youcheng,Zhang ^[5]

作者单位： Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China. ^[1] Provincial-Level Key Laboratory of Molecular Medicine of Major Diseases and Study on Prevention and Treatment of Traditional Chinese Medicine, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, Gansu Province, China. ^[2] Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China; People's Hospital affiliated with Chongqing Three Gorges Medical Higher Specialized School, Chongqing 404100, China. ^[3] Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China; Department of Hepatology, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China. ^[4] Department of General Surgery, Lanzhou University Second Hospital, Lanzhou 730030, Gansu Province, China. Electronic address: zhangyouchengphd@163.com. ^[5]

关键词 AFP HCC LATS2 TEAD1 Tumor cell-intrinsic PD-1 YAP

主题词人类(Humans);癌, 肝细胞(Carcinoma, Hepatocellular);甲胎蛋白类(alpha-Fetoproteins);肝肿瘤(Liver Neoplasms);转录因子(Transcription Factors);衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)

DOI 10.1016/j.bbagen.2024.130592

PMID 38395204

发布时间 2024-03-29

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Biochimica et biophysica acta. General subjects

2024年1868卷5期

130592页

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Alpha-fetoprotein upregulates hepatocellular carcinoma cell-intrinsic PD-1 expression through the LATS2/YAP/TEAD1 pathway.

Biochimica et biophysica acta. General subjects

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Biochimica et biophysica acta. General subjects

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Alpha-fetoprotein upregulates hepatocellular carcinoma cell-intrinsic PD-1 expression through the LATS2/YAP/TEAD1 pathway.

Biochimica et biophysica acta. General subjects

相似文献

Biochimica et biophysica acta. General subjects

相关期刊

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