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Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of <i>C. asiatica</i> Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.

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作者单位: Department of Chemistry, Oregon State University, Corvallis, OR 97331, USA.;BENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.;Life Sciences Institute, University of British Columbia, Vancouver, BC V6T 1Z4, Canada. [1] Department of Chemistry, Oregon State University, Corvallis, OR 97331, USA. [2] Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR 97331, USA.;School of Chemical, Biological, and Environmental Engineering, Oregon State University, 116 Johnson Hall, 105 SW 26th Street, Corvallis, OR 97331, USA. [3] Department of Statistics, Oregon State University, Corvallis, OR 97331, USA. [4] Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA. [5] BENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.;Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA. [6] Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.;Parkinson's Disease Research Education and Clinical Care Center, Veterans' Administration Portland Health Care System, Portland, OR 97239, USA. [7] BENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.;Department of Pharmaceutical Sciences, Oregon State University, Corvallis, OR 97331, USA.;Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA. [8] Department of Chemistry, Oregon State University, Corvallis, OR 97331, USA.;BENFRA Botanical Dietary Supplements Research Center, Oregon Health & Science University, Portland, OR 97239, USA.;Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA. [9]
DOI 10.3390/molecules29040838
PMID 38398590
发布时间 2024-09-28
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Molecules (Basel, Switzerland)

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