Influence of Desialylation on the Drug Binding Affinity of Human Alpha-1-Acid Glycoprotein Assessed by Microscale Thermophoresis.

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作者： Tino,Šeba ^[1] ; Robert,Kerep ^[1] ; Tin,Weitner ^[1] ; Dinko,Šoić ^[2] ; Toma,Keser ^[2] ; Gordan,Lauc ^[2] ; Mario,Gabričević ^[1]

作者单位： Department of General and Inorganic Chemistry, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10000 Zagreb, Croatia. ^[1] Department of Biochemistry and Molecular Biology, Faculty of Pharmacy and Biochemistry, University of Zagreb, A. Kovačića 1, 10000 Zagreb, Croatia. ^[2]

关键词 alpha-1-acid glycoprotein desialylation equilibrium binding affinity microscale thermophoresis plasma protein binding

DOI 10.3390/pharmaceutics16020230

PMID 38399284

发布时间 2024-02-27

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