Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment.

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第一作者： Xue-Yan,He

第一单位： Cold Spring Harbor Laboratory, Cancer Center, Cold Spring Harbor, NY 11724, USA.

作者： Xue-Yan,He ^[1] ; Yuan,Gao ^[1] ; David,Ng ^[1] ; Evdokia,Michalopoulou ^[1] ; Shanu,George ^[1] ; Jose M,Adrover ^[1] ; Lijuan,Sun ^[1] ; Jean,Albrengues ^[2] ; Juliane,Daßler-Plenker ^[1] ; Xiao,Han ^[3] ; Ledong,Wan ^[1] ; Xiaoli Sky,Wu ^[3] ; Longling S,Shui ^[3] ; Yu-Han,Huang ^[1] ; Bodu,Liu ^[1] ; Chang,Su ^[4] ; David L,Spector ^[1] ; Christopher R,Vakoc ^[1] ; Linda,Van Aelst ^[1] ; Mikala,Egeblad ^[5]

作者单位： Cold Spring Harbor Laboratory, Cancer Center, Cold Spring Harbor, NY 11724, USA. ^[1] Cold Spring Harbor Laboratory, Cancer Center, Cold Spring Harbor, NY 11724, USA; Université Côte d'Azur, CNRS UMR7284, INSERM U1081, Institute for Research on Cancer and Aging, Nice (IRCAN), Nice, France. ^[2] Cold Spring Harbor Laboratory, Cancer Center, Cold Spring Harbor, NY 11724, USA; Graduate Program in Genetics, Stony Brook University, Stony Brook, NY 11794, USA. ^[3] Department of Population Health Sciences, Weill Cornell Medicine, New York, NY 10065, USA; Institute of Artificial Intelligence for Digital Health, Weill Cornell Medicine, Cornell University, New York, NY 10065, USA. ^[4] Cold Spring Harbor Laboratory, Cancer Center, Cold Spring Harbor, NY 11724, USA. Electronic address: mikala.egeblad@jhmi.edu. ^[5]

关键词 breast cancer chronic stress glucocorticoids metastasis metastatic niche neutrophil extracellular traps tumor microenvironment tumor-host interactions

主题词人类(Humans);动物(Animals);小鼠(Mice);中性白细胞(Neutrophils);肺肿瘤(Lung Neoplasms);肺(Lung);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.ccell.2024.01.013

PMID 38402610

发布时间 2025-01-21

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