PHPB ameliorates memory deficits and reduces oxidative injury in Alzheimer's disease mouse model by activating Nrf2 signaling pathway.

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第一作者： Nian-Ying,Shang

第一单位： State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China.

作者： Nian-Ying,Shang ^[1] ; Long-Jian,Huang ^[1] ; Jia-Qi,Lan ^[1] ; Yu-Ying,Kang ^[1] ; Jing-Shu,Tang ^[1] ; Hong-Yue,Wang ^[1] ; Xin-Nan,Li ^[1] ; Zhuo,Sun ^[1] ; Qiu-Yu,Chen ^[1] ; Meng-Yao,Liu ^[1] ; Zi-Peng,Wen ^[1] ; Xin-Hong,Feng ^[2] ; Lei,Wu ^[1] ; Ying,Peng ^[3]

作者单位： State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. ^[1] Department of Neurology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, China. ^[2] State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100050, China. ypeng@imm.ac.cn. ^[3]

关键词 Alzheimer disease NF-E2-related factor 2 cognition oxidative stress potassium 2-(1-hydroxypentyl)-benzoate (PHPB)