Investigating the efficacy and safety of olanzapine prophylaxis for opioid-induced nausea and vomiting (JORTC-PAL20): a study protocol for an open-label, single-arm exploratory study.

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第一作者： Eriko,Satomi

第一单位： Palliative Medicine, National Cancer Center Japan, Tokyo, Japan okires@gmail.com.;Palliative Medicine, Juntendo University School of Medicine, Graduate School of Medicine, Tokyo, Japan.

作者： Eriko,Satomi ^[1] ; Tomomi,Kobayashi ^[2] ; Ayaka,Ishikawa ^[2] ; Sayaka,Arakawa ^[2] ; Hiroto,Ishiki ^[2] ; Koji,Amano ^[3] ; Naomi,Sakiyama ^[4] ; Keisuke,Ariyoshi ^[5] ; Kota,Kihara ^[6] ; Shunsuke,Oyamada ^[7] ; Akio,Mizushima ^[8]

作者单位： Palliative Medicine, National Cancer Center Japan, Tokyo, Japan okires@gmail.com.;Palliative Medicine, Juntendo University School of Medicine, Graduate School of Medicine, Tokyo, Japan. ^[1] Palliative Medicine, National Cancer Center Japan, Tokyo, Japan. ^[2] Palliative Medicine, Osaka University, Oaska, Japan. ^[3] Pharmacy, National Cancer Center Hospital, Tokyo, Japan. ^[4] Data Center, Japanese Organisation for Research and Treatment of Cancer, Tokyo, Japan. ^[5] Secretary, Japanese Organisation for Research and Treatment of Cancer, Tokyo, Japan. ^[6] Biostatictics, Japanese Organisation for Research and Treatment of Cancer, Tokyo, Japan. ^[7] Palliative Medicine, Juntendo University School of Medicine, Graduate School of Medicine, Tokyo, Japan. ^[8]

关键词 Adult palliative care Adverse events Cancer pain

主题词人类(Humans);止吐药(Antiemetics);镇痛药, 阿片类(Analgesics, Opioid);催吐药(Emetics);呕吐(Vomiting);恶心(Nausea)

DOI 10.1136/bmjopen-2023-076575

PMID 38417963

发布时间 2024-12-23

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准确一般字义偏差语意偏离译文作用小提交