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Generation of Fel d 1 chain 2 genome-edited cats by CRISPR-Cas9 system.

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第一作者： Sang Ryeul,Lee

第一单位： Animal, Dairy, and Veterinary Sciences Department, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, 84322, USA.;Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA.

作者： Sang Ryeul,Lee ^[1] ; Kyung-Lim,Lee ^[2] ; Seok-Hwan,Song ^[2] ; Myeong-Don,Joo ^[3] ; Seo-Hyun,Lee ^[3] ; Ji-Su,Kang ^[3] ; Seon-Min,Kang ^[3] ; Muhammad,Idrees ^[3] ; Jae-Wook,Kim ^[2] ; Il-Keun,Kong ^[4]

作者单位： Animal, Dairy, and Veterinary Sciences Department, College of Agriculture and Applied Sciences, Utah State University, Logan, UT, 84322, USA.;Moores Cancer Center, University of California, San Diego, La Jolla, CA, 92093, USA. ^[1] TheKingKong Corp. Ltd., Gyeongsang National University, Jinju, Gyeongnam Province, 52828, Republic of Korea. ^[2] Division of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju, Gyeongnam Province, 52828, Republic of Korea. ^[3] TheKingKong Corp. Ltd., Gyeongsang National University, Jinju, Gyeongnam Province, 52828, Republic of Korea. ikong@gnu.ac.kr.;Division of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju, Gyeongnam Province, 52828, Republic of Korea. ikong@gnu.ac.kr.;Institute of Agriculture and Life Science, Gyeongsang National University, Jinju, Gyeongnam Province, 52828, Republic of Korea. ikong@gnu.ac.kr. ^[4]

关键词 Allergen CH2 CRISPR-Cas9 Fel d 1 Genome-edited cats Hypoallergenic cats

医学主题词猫(Cats);动物(Animals);人类(Humans);超敏反应(Hypersensitivity);变应原(Allergens);哮喘(Asthma);酶联免疫吸附测定(Enzyme-Linked Immunosorbent Assay)

DOI 10.1038/s41598-024-55464-0

PMID 38424152

发布时间 2024-03-04

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