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Nrf2 activation by neferine mitigates microglial neuroinflammation after subarachnoid hemorrhage through inhibiting TAK1-NF-κB signaling.

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第一作者： Xiaotian,Zhang

第一单位： Department of Neurosurgery, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China.

作者： Xiaotian,Zhang ^[1] ; Jun,Li ^[1] ; Changchun,Cao ^[2] ; Zhichao,Liu ^[1] ; Qiushi,Chen ^[1] ; Zhijiang,Gu ^[1] ; Weijie,Wang ^[1] ; Dazhao,Fang ^[1] ; QianQian,Ge ^[3] ; Lianshu,Ding ^[4] ; Cong,Pang ^[5] ; Xiaodong,Wang ^[6]

作者单位： Department of Neurosurgery, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China. ^[1] Department of Pharmacy, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China. ^[2] Department of Gynecology, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China. ^[3] Department of Neurosurgery, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China. Electronic address: dlshu@njmu.edu.cn. ^[4] Department of Neurosurgery, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China. Electronic address: congpang_2017@126.com. ^[5] Department of Neurosurgery, The Affiliated Huaian NO.1 People's Hospital of Nanjing Medical University, No. 1 Huanghe Road West, Huaian, Jiangsu 223300, China. Electronic address: wxdxa19800@126.com. ^[6]

关键词 Early brain injury Microglia Neuroinflammation Nrf2 Subarachnoid hemorrhage TAK1