Neutralization of SARS-CoV-2 BA.2.86 and JN.1 by CF501 adjuvant-enhanced immune responses targeting the conserved epitopes in ancestral RBD.

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第一作者： Zezhong,Liu

第一单位： Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, School of Pharmacy, Shanghai Medical College, Fudan University, Shanghai 200032, China. Electronic address: zezhongliu@fudan.edu.cn.

作者： Zezhong,Liu ^[1] ; Jie,Zhou ^[2] ; Weijie,Wang ^[2] ; Guangxu,Zhang ^[2] ; Lixiao,Xing ^[2] ; Keqiang,Zhang ^[2] ; Yuanzhou,Wang ^[2] ; Wei,Xu ^[2] ; Qian,Wang ^[2] ; Qiuhong,Man ^[3] ; Qiao,Wang ^[2] ; Tianlei,Ying ^[2] ; Yun,Zhu ^[4] ; Shibo,Jiang ^[5] ; Lu,Lu ^[6]

作者单位： Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, School of Pharmacy, Shanghai Medical College, Fudan University, Shanghai 200032, China. Electronic address: zezhongliu@fudan.edu.cn. ^[1] Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, School of Pharmacy, Shanghai Medical College, Fudan University, Shanghai 200032, China. ^[2] Department of Laboratory Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, Shanghai 200032, China. ^[3] National Key Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China. ^[4] Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, School of Pharmacy, Shanghai Medical College, Fudan University, Shanghai 200032, China. Electronic address: shibojiang@fudan.edu.cn. ^[5] Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, School of Pharmacy, Shanghai Medical College, Fudan University, Shanghai 200032, China. Electronic address: lul@fudan.edu.cn. ^[6]

关键词 JN.1 SARS-CoV-2 STING agonist adjuvant conserved epitopes coronavirus vaccine

主题词动物(Animals);猕猴(Macaca mulatta);表位(Epitopes)

DOI 10.1016/j.xcrm.2024.101445

PMID 38428429

发布时间 2024-04-03

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Cell reports. Medicine

2024年5卷3期

101445页

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Neutralization of SARS-CoV-2 BA.2.86 and JN.1 by CF501 adjuvant-enhanced immune responses targeting the conserved epitopes in ancestral RBD.

Cell reports. Medicine

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Neutralization of SARS-CoV-2 BA.2.86 and JN.1 by CF501 adjuvant-enhanced immune responses targeting the conserved epitopes in ancestral RBD.

Cell reports. Medicine

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Cell reports. Medicine

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