Mood disturbances in newly diagnosed Parkinson's Disease patients reflect intrathecal inflammation.

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作者： Mario,Stampanoni Bassi ^[1] ; Luana,Gilio ^[2] ; Giovanni,Galifi ^[1] ; Fabio,Buttari ^[1] ; Ettore,Dolcetti ^[1] ; Antonio,Bruno ^[1] ; Lorena,Belli ^[1] ; Nicola,Modugno ^[1] ; Roberto,Furlan ^[3] ; Annamaria,Finardi ^[3] ; Georgia,Mandolesi ^[4] ; Alessandra,Musella ^[4] ; Diego,Centonze ^[5] ; Enrica,Olivola ^[1]

作者单位： Unit of Neurology, IRCCS Neuromed, Pozzilli, IS, Italy. ^[1] Unit of Neurology, IRCCS Neuromed, Pozzilli, IS, Italy; Faculty of Psychology, Uninettuno Telematic International University, Rome, Italy. ^[2] Clinical Neuroimmunology Unit, Institute of Experimental Neurology (INSpe), Division of Neuroscience, San Raffaele Scientific Institute, Milan, Italy. ^[3] Synaptic Immunopathology Lab, IRCCS San Raffaele Roma, Italy; Department of Human Sciences and Quality of Life Promotion, University of Rome San Raffaele, Italy. ^[4] Unit of Neurology, IRCCS Neuromed, Pozzilli, IS, Italy; Laboratory of Synaptic Immunopathology, Department of Systems Medicine, Tor Vergata University, Rome, Italy. Electronic address: centonze@uniroma2.it. ^[5]

关键词 Anxiety Cerebrospinal fluid Depression Inflammatory molecules Mood disorders Nonmotor symptoms Parkinson's disease