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Hybrid capture shotgun sequencing detected unexpected viruses in the cerebrospinal fluid of children with acute meningitis and encephalitis.

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第一作者： Cristian,Launes

第一单位： Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Barcelona, Spain.;CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.;Departament de Medicina i Especialitats Medicoquirúrgiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain.

作者： Cristian,Launes ^[1] ; Juan,Camacho ^[2] ; Marina,Pons-Espinal ^[3] ; F Xavier,López-Labrador ^[4] ; Cristina,Esteva ^[3] ; María,Cabrerizo ^[5] ; María Dolores,Fernández-García ^[5] ; Marta,Fogeda ^[6] ; Josefa,Masa-Calles ^[7] ; Noemí,López-Perea ^[7] ; Juan Emilio,Echevarría ^[5] ; Carmen,Muñoz-Almagro ^[8] ; David,Tarragó ^[9]

作者单位： Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Barcelona, Spain.;CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.;Departament de Medicina i Especialitats Medicoquirúrgiques, Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona, Barcelona, Spain. ^[1] Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda- Pozuelo km 2, 28220, Majadahonda, Spain. ^[2] Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Barcelona, Spain.;CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain. ^[3] CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.;Genomics & Health Department, FISABIO-Public Health Foundation, Valencia, Spain.;Department of Microbiology and Ecology, Medical School, University of Valencia, Valencia, Spain. ^[4] CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.;Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda- Pozuelo km 2, 28220, Majadahonda, Spain. ^[5] Hologic Iberia SL, Madrid, Spain. ^[6] CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.;Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Avda Monforte de Lemos 5, Madrid, Spain. ^[7] Institut de Recerca Sant Joan de Déu, Hospital Sant Joan de Déu, Barcelona, Spain.;CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain.;Department of Medicine, Universitat Internacional de Catalunya, Barcelona, Spain. ^[8] CIBER Epidemiology and Public Health (CIBERESP), Madrid, Spain. davtarrago@isciii.es.;Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda- Pozuelo km 2, 28220, Majadahonda, Spain. davtarrago@isciii.es. ^[9]

关键词 BK virus, Epstein-Barr virus (EBV)Cerebrospinal fluid (CSF)Human endogenous retrovirus K-113 (HERV-K113)Human herpesvirus 7 (HHV-7)Paediatric meningitis and/or encephalitis (M/ME)Undiagnosed viral meningoencephalitis Viral metagenomics