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Analyzing postprandial metabolomics data using multiway models: a simulation study.

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第一作者： Lu,Li

第一单位： Department of Data Science and Knowledge Discovery, Simula Metropolitan Center for Digital Engineering, Oslo, Norway. lu@simula.no.

作者： Lu,Li ^[1] ; Shi,Yan ^[2] ; Barbara M,Bakker ^[3] ; Huub,Hoefsloot ^[4] ; Bo,Chawes ^[5] ; David,Horner ^[5] ; Morten A,Rasmussen ^[6] ; Age K,Smilde ^[7] ; Evrim,Acar ^[8]

作者单位： Department of Data Science and Knowledge Discovery, Simula Metropolitan Center for Digital Engineering, Oslo, Norway. lu@simula.no. ^[1] Department of Data Science and Knowledge Discovery, Simula Metropolitan Center for Digital Engineering, Oslo, Norway. ^[2] Laboratory of Pediatrics, Section Systems Medicine and Metabolic Signalling, Center for Liver, Digestive and Metabolic Disease, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. ^[3] Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands. ^[4] Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. ^[5] Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.;Department of Food Science, University of Copenhagen, Copenhagen, Denmark. ^[6] Department of Data Science and Knowledge Discovery, Simula Metropolitan Center for Digital Engineering, Oslo, Norway.;Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands. ^[7] Department of Data Science and Knowledge Discovery, Simula Metropolitan Center for Digital Engineering, Oslo, Norway. evrim@simula.no. ^[8]

关键词 CANDECOMP/PARAFAC (CP)Meal challenge test Postprandial metabolomics data Principal component analysis (PCA)Tensor factorizations (multiway data analysis)Time-resolved metabolomics data Whole-body metabolic model

医学主题词人类(Humans);代谢组学(Metabolomics);计算机模拟(Computer Simulation);健康状况(Health Status);医学(Medicine)

DOI 10.1186/s12859-024-05686-w

PMID 38438850

发布时间 2024-03-07

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