Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy.

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作者： Hesong,Zou ^[1] ; Wei,Liu ^[2] ; Xiaojuan,Wang ^[1] ; Yi,Wang ^[2] ; Chunyang,Wang ^[3] ; Chen,Qiu ^[4] ; Huimin,Liu ^[5] ; Dandan,Shan ^[1] ; Ting,Xie ^[2] ; Wenyang,Huang ^[4] ; Weiwei,Sui ^[5] ; Shuhua,Yi ^[1] ; Gang,An ^[2] ; Yan,Xu ^[1] ; Tonghui,Ma ^[2] ; Jianxiang,Wang ^[1] ; Lugui,Qiu ^[2] ; Dehui,Zou ^[1]

作者单位： State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. ^[1] Tianjin Institutes of Health Science, Tianjin, China. ^[2] Tianjin Key Laboratory of Cell Therapy for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China. ^[3] Jichen Biotechnology Co, Ltd, Hangzhou, Zhejiang, China. ^[4] Genecn-Biotech Co, Ltd, Hangzhou, Zhejiang, China. ^[5] State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China zoudehui@ihcams.ac.cn qiulg@ihcams.ac.cn wangjx@ihcams.ac.cn. ^[6]

关键词 Chimeric antigen receptor - CAR Immunotherapy Lymphoma

主题词人类(Humans);免疫疗法, 过继(Immunotherapy, Adoptive);肿瘤复发, 局部(Neoplasm Recurrence, Local);基因组学(Genomics);淋巴瘤, 大B细胞, 弥漫性(Lymphoma, Large B-Cell, Diffuse)

DOI 10.1136/jitc-2023-008450

PMID 38443094

发布时间 2024-06-05

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Journal for immunotherapy of cancer

2024年12卷3期

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Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy.

Journal for immunotherapy of cancer

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Dynamic monitoring of circulating tumor DNA reveals outcomes and genomic alterations in patients with relapsed or refractory large B-cell lymphoma undergoing CAR T-cell therapy.

Journal for immunotherapy of cancer

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Journal for immunotherapy of cancer

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