α-Melanocyte-stimulating hormone alleviates pathological cardiac remodeling via melanocortin 5 receptor.

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第一作者： Anni,Suominen

第一单位： Research Centre for Integrative Physiology & Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland.;Drug Research Doctoral Programme (DRDP), University of Turku, Turku, Finland.

作者： Anni,Suominen ^[1] ; Guillem,Saldo Rubio ^[2] ; Saku,Ruohonen ^[2] ; Zoltán,Szabó ^[3] ; Lotta,Pohjolainen ^[4] ; Bishwa,Ghimire ^[5] ; Suvi T,Ruohonen ^[2] ; Karla,Saukkonen ^[2] ; Jani,Ijas ^[2] ; Sini,Skarp ^[3] ; Leena,Kaikkonen ^[3] ; Minying,Cai ^[6] ; Sharon L,Wardlaw ^[7] ; Heikki,Ruskoaho ^[4] ; Virpi,Talman ^[4] ; Eriika,Savontaus ^[8] ; Risto,Kerkelä ^[9] ; Petteri,Rinne ^[10]

作者单位： Research Centre for Integrative Physiology & Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland.;Drug Research Doctoral Programme (DRDP), University of Turku, Turku, Finland. ^[1] Research Centre for Integrative Physiology & Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland. ^[2] Research Unit of Biomedicine and Internal Medicine, Department of Pharmacology and Toxicology, University of Oulu, Oulu, Finland. ^[3] Drug Research Program and Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland. ^[4] Institute for Molecular Medicine Finland (FIMM), HiLIFE Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland.;Faculty of Medicine, University of Turku, Turku, Finland. ^[5] Department of Chemistry and Biochemistry, University of Arizona, Tucson, AZ, USA. ^[6] Department of Medicine, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA. ^[7] Research Centre for Integrative Physiology & Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland.;Turku Center for Disease Modeling, University of Turku, Turku, Finland.;Unit of Clinical Pharmacology, Turku University Hospital, Turku, Finland. ^[8] Research Unit of Biomedicine and Internal Medicine, Department of Pharmacology and Toxicology, University of Oulu, Oulu, Finland.;Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.;Biocenter Oulu, University of Oulu, Oulu, Finland. ^[9] Research Centre for Integrative Physiology & Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland. pperin@utu.fi.;Turku Center for Disease Modeling, University of Turku, Turku, Finland. pperin@utu.fi. ^[10]

关键词 Fibrosis Heart Failure Hypertrophy Melanocortin Receptor Melanocyte-stimulating Hormone