A T cell-based SARS-CoV-2 spike protein vaccine provides protection without antibodies.

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第一作者： Juan,Shi

第一单位： Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.

作者： Juan,Shi ^[1] ; Jian,Zheng ^[2] ; Xiujuan,Zhang ^[3] ; Wanbo,Tai ^[3] ; Ryan,Compas ^[4] ; Jack,Deno ^[4] ; Natalie,Jachym ^[4] ; Abhishek K,Verma ^[2] ; Gang,Wang ^[1] ; Xiaoqing,Guan ^[1] ; Abby E,Odle ^[2] ; Yushun,Wan ^[5] ; Fang,Li ^[5] ; Stanley,Perlman ^[6] ; Liang,Qiao ^[2] ; Lanying,Du ^[4]

作者单位： Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA. ^[1] Department of Microbiology and Immunology, and Department of Pediatrics, University of Iowa, Iowa City, Iowa, USA. ^[2] Lindsley F. Kimball Research Institute, New York Blood Center, New York, New York, USA. ^[3] Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois, USA. ^[4] Department of Pharmacology, University of Minnesota Medical School, Minneapolis, Minnesota, USA. ^[5] Center for Coronavirus Research, University of Minnesota, Minneapolis, Minnesota, USA. ^[6]

关键词 Adaptive immunity COVID-19 T cells Vaccines

主题词动物(Animals);人类(Humans);小鼠(Mice);疾病大流行(Pandemics);抗体(Antibodies);疫苗(Vaccines)

DOI 10.1172/jci.insight.155789

PMID 38456504

发布时间 2024-03-29

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A T cell-based SARS-CoV-2 spike protein vaccine provides protection without antibodies.

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