The modulatory effects of large and small extracellular vesicles from normal human urine on calcium oxalate crystallization, growth, aggregation, adhesion on renal cells, and invasion through extracellular matrix: An in vitro study.

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作者： Sudarat,Hadpech ^[1] ; Sakdithep,Chaiyarit ^[1] ; Somsakul,Phuangkham ^[1] ; Sirirat,Sukphan ^[1] ; Visith,Thongboonkerd ^[2]

作者单位： Medical Proteomics Unit, Research Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. ^[1] Medical Proteomics Unit, Research Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. Electronic address: thongboonkerd@dr.com. ^[2]

关键词 CaOx Exosomes Inhibitor Kidney stone Microvesicles Modulator Urine uEVs

主题词人类(Humans);草酸钙(Calcium Oxalate);结晶(Crystallization);肾结石(Kidney Calculi);蛋白质类(Proteins);细胞外基质(Extracellular Matrix);芘类(Pyrenes)

DOI 10.1016/j.biopha.2024.116393

PMID 38461684

发布时间 2024-03-27

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