Effect of sacubitril/valsartan on the hypertensive heart in continuous light-induced and lactacystin-induced pre-hypertension: Interactions with the renin-angiotensin-aldosterone system.

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作者： Fedor,Simko ^[1] ; Peter,Stanko ^[2] ; Kristina,Repova ^[3] ; Tomas,Baka ^[3] ; Kristina,Krajcirovicova ^[3] ; Silvia,Aziriova ^[3] ; Oliver,Domenig ^[4] ; Stefan,Zorad ^[5] ; Michaela,Adamcova ^[6] ; Ludovit,Paulis ^[7]

作者单位： Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava 81108, Slovak Republic; 3rd Department of Internal Medicine, Faculty of Medicine, Comenius University, Bratislava 83305, Slovak Republic; Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava 84505, Slovak Republic. Electronic address: fedor.simko@fmed.uniba.sk. ^[1] Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava 81108, Slovak Republic; Department of Pneumology, Phthisiology and Functional Diagnostics, Slovak Medical University and Bratislava University Hospital, Bratislava, Slovak Republic. ^[2] Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava 81108, Slovak Republic. ^[3] Attoquant Diagnostics, Vienna 1110, Austria. ^[4] Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava 84505, Slovak Republic. ^[5] Department of Physiology, Charles University, Faculty of Medicine in Hradec Kralove, Hradec Kralove 50003, Czech Republic. ^[6] Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava 81108, Slovak Republic; Centre of Experimental Medicine SAS, Institute of Normal and Pathological Physiology, Slovak Academy of Sciences, Bratislava 813 71, Slovak Republic. ^[7]

关键词 Angiotensin/aldosterone Continuous light Lactacystin Pre-hypertension Remodelling Sacubitril/valsartan/ARNI