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CDKN1A regulation on chondrogenic differentiation of human chondrocytes in osteoarthritis through single-cell and bulk sequencing analysis.

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第一作者： Chao,Fang

第一单位： Department of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China.

作者： Chao,Fang ^[1] ; Shanbang,Zhu ^[2] ; Rui,Zhong ^[1] ; Gang,Yu ^[1] ; Shuai,Lu ^[1] ; Zhilin,Liu ^[1] ; Jingyu,Gao ^[1] ; Chengyuan,Yan ^[1] ; Yingming,Wang ^[1] ; Xinzhe,Feng ^[3]

作者单位： Department of Orthopedics, The First Affiliated Hospital of USTC, Hefei, 230001, China. ^[1] Department of Orthopedics, Affiliated Jinling Hospital, Medical School of Nanjing University, No 305 Zhongshandonglu Road, Nanjing, 210002, China. ^[2] Department of Joint Bone Disease Surgery, Changhai Hospital, Naval Medical University, Shanghai, 200433, China. ^[3]

关键词 Boruta algorithm Least absolute shrinkage and selection operator (LASSO)Osteoarthritis (OA)Principal component analysis (PCA)Programmed cell death related genes T-distributed stochastic neighbor embedding (t-SNE)Weighted gene co-expression network analysis (WGCNA)

DOI 10.1016/j.heliyon.2024.e27466

PMID 38463824

发布时间 2024-03-12

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CDKN1A regulation on chondrogenic differentiation of human chondrocytes in osteoarthritis through single-cell and bulk sequencing analysis.

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CDKN1A regulation on chondrogenic differentiation of human chondrocytes in osteoarthritis through single-cell and bulk sequencing analysis.

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