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The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats.

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第一作者： Bindu,Kodati

第一单位： Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States.;North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, United States.

作者： Bindu,Kodati ^[1] ; Wei,Zhang ^[1] ; Shaoqing,He ^[2] ; Jennifer H,Pham ^[1] ; Kallen J,Beall ^[3] ; Zoe E,Swanger ^[4] ; Vignesh R,Krishnamoorthy ^[5] ; Payton E,Harris ^[6] ; Trent,Hall ^[7] ; Ashley V,Tran ^[8] ; Renuka M,Chaphalkar ^[9] ; Sai H,Chavala ^[10] ; Dorota L,Stankowska ^[1] ; Raghu R,Krishnamoorthy ^[1]

作者单位： Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, United States.;North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, TX, United States. ^[1] Department of Pathology, Children's Health at Dallas, Dallas, TX, United States. ^[2] Department of General Surgery, Honor Health, Phoenix, AZ, United States. ^[3] Texas College of Osteopathic Medicine, University of North Texas Health Science Center, Fort Worth, TX, United States. ^[4] Department of Cell and Molecular Pharmacology, Loyola University, Maywood, IL, United States. ^[5] Department of Graduate Medical Education, Medical City, Fort Worth, TX, United States. ^[6] Williams College, Williamstown, MA, United States. ^[7] School of Natural Sciences and Mathematics, The University of Texas at Dallas, Richardson, TX, United States. ^[8] Department of Ophthalmology, School of Medicine, University of California, San Francisco, CA, United States. ^[9] Department of Surgery, Burnett School of Medicine at Texas Christian University (TCU), Fort Worth, TX, United States. ^[10]

关键词 endothelins glaucoma macitentan neuroprotection vasoconstriction

DOI 10.3389/fopht.2023.1185755

PMID 38464735

发布时间 2024-03-13

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Frontiers in ophthalmology

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The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats.

Frontiers in ophthalmology

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Frontiers in ophthalmology

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The endothelin receptor antagonist macitentan ameliorates endothelin-mediated vasoconstriction and promotes the survival of retinal ganglion cells in rats.

Frontiers in ophthalmology

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Frontiers in ophthalmology

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