Restriction of Glycolysis Increases Serial Killing Capacity of Natural Killer Cells.

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作者： Lea Katharina,Picard ^[1] ; Jens Alexander,Niemann ^[1] ; Elisabeth,Littwitz-Salomon ^[2] ; Herbert,Waldmann ^[3] ; Carsten,Watzl ^[4]

作者单位： Department for Immunology, Leibniz Research Centre for Working Environment and Human Factors at TU Dortmund (IfADo), D-44139 Dortmund, Germany. ^[1] Institute for Virology, Institute for Translational HIV Research, University Hospital Essen, D-45147 Essen, Germany. ^[2] Max Planck Institute of Molecular Physiology, D-44227 Dortmund, Germany. ^[3] Faculty of Chemistry, Chemical Biology, Technical University Dortmund, D-44227 Dortmund, Germany. ^[4]

关键词 cytokines cytotoxicity degranulation glucose transporter metabolism

主题词人类(Humans);杀伤细胞, 天然(Killer Cells, Natural);肿瘤(Neoplasms);糖酵解(Glycolysis);葡萄糖(Glucose);肿瘤微环境(Tumor Microenvironment)

DOI 10.3390/ijms25052917

PMID 38474166

发布时间 2024-03-15

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