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首页> Molecules (Basel, Switzerland)> In Vitro and In Silico of Cholinesterases Inhibition and In Vitro and In Vivo Anti-Melanoma Activity Investigations of Extracts Obtained from Selected <i>Berberis</i> Species.

In Vitro and In Silico of Cholinesterases Inhibition and In Vitro and In Vivo Anti-Melanoma Activity Investigations of Extracts Obtained from Selected <i>Berberis</i> Species.

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作者： Tomasz,Tuzimski ^[1] ; Anna,Petruczynik ^[2] ; Barbara,Kaproń ^[3] ; Tomasz,Plech ^[3] ; Anna,Makuch-Kocka ^[4] ; Daria,Janiszewska ^[3] ; Mateusz,Sugajski ^[4] ; Bogusław,Buszewski ^[5] ; Małgorzata,Szultka-Młyńska ^[5]

作者单位： Department of Physical Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland. ^[1] Department of Inorganic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland. ^[2] Department of Clinical Genetics, Faculty of Medicine, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland. ^[3] Department of Pharmacology, Faculty of Health Sciences, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland. ^[4] Department of Environmental Chemistry and Bioanalytics, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Torun, Poland. ^[5]

关键词 Berberis species Danio rerio larvae xenograft model HPLC-DAD LC-MS/MS cytotoxic activity inhibition of cholinesterase activity molecular docking

主题词人类(Humans);小檗碱(Berberine);乙酰胆碱酯酶(Acetylcholinesterase);小檗属(Berberis);丁酰胆碱酯酶(Butyrylcholinesterase);胆碱酯酶抑制剂(Cholinesterase Inhibitors);黑色素瘤(Melanoma);生物碱类(Alkaloids);植物提取物(Plant Extracts);抗肿瘤药(Antineoplastic Agents)

DOI 10.3390/molecules29051048

PMID 38474561

发布时间 2024-03-15

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Molecules (Basel, Switzerland)

Molecules (Basel, Switzerland)

2024年29卷5期

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