Continuous evolution of compact protein degradation tags regulated by selective molecular glues.

导出 OA

翻译打印收藏纠错

作者： Jaron A M,Mercer ^[1] ; Stephan J,DeCarlo ^[2] ; Shourya S,Roy Burman ^[3] ; Vedagopuram,Sreekanth ^[1] ; Andrew T,Nelson ^[2] ; Moritz,Hunkeler ^[3] ; Peter J,Chen ^[4] ; Katherine A,Donovan ^[5] ; Praveen,Kokkonda ^[6] ; Praveen K,Tiwari ^[7] ; Veronika M,Shoba ^[8] ; Arghya,Deb ^[1] ; Amit,Choudhary ^[2] ; Eric S,Fischer ^[3] ; David R,Liu ^[4]

作者单位： Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. ^[1] Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA. ^[2] Howard Hughes Medical Institute, Harvard University, Cambridge, MA 02138, USA. ^[3] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. ^[4] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. ^[5] Chemical Biology and Therapeutics Science, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. ^[6] Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. ^[7] Divisions of Renal Medicine and Engineering, Brigham and Women's Hospital, Boston, MA 02115, USA. ^[8]