Etomidate enhances cerebellar CF-PC synaptic plasticity through CB1 receptor/PKA cascade in vitro in mice.

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作者： Guang-Gao,Li ^[1] ; Ying-Han,Xu ^[1] ; Ming-Ze,Sun ^[2] ; Yan-Hua,Bing ^[3] ; Wen-Zhe,Jin ^[4] ; De-Lai,Qiu ^[5]

作者单位： Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji City, Jilin Province 133002, China; Department of Orthopedics, Affiliated Hospital of Yanbian University, Yanji City, Jilin Province 133000, China. ^[1] Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji City, Jilin Province 133002, China; Institute of Brain Science, Jilin Medical University, Jilin City, Jilin Province 132013, China. ^[2] Functional Experiment Center, College of Medicine, Yanbian University, Yanji City, Jilin Province 133000, China. ^[3] Department of Pain, Affiliated Hospital of Yanbian University, Yanji City, Jilin Province 133000, China. ^[4] Department of Physiology and Pathophysiology, College of Medicine, Yanbian University, Yanji City, Jilin Province 133002, China; Institute of Brain Science, Jilin Medical University, Jilin City, Jilin Province 132013, China; Department of Physiology, College of Basic Medicine, Jilin Meidcal University, Jilin City, Jilin Province 132013, China. Electronic address: dlqiu@ybu.edu.cn. ^[5]

关键词 Cerebellar climbing fiber-Purkinje cell synapses Etomidate Long-term depression NMDA receptor Pharmacology Protein kinase A Whole-cell recording