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Identification of immunological patterns characterizing immune-related psoriasis reactions in oncological patients in therapy with anti-PD-1 checkpoint inhibitors.

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第一作者： Martina,Morelli

第一单位： Experimental Immunology Laboratory, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy.

作者： Martina,Morelli ^[1] ; Maria Luigia,Carbone ^[1] ; Giovanni Luca,Scaglione ^[1] ; Claudia,Scarponi ^[1] ; Valentina,Di Francesco ^[1] ; Sabatino,Pallotta ^[2] ; Federica,De Galitiis ^[3] ; Siavash,Rahimi ^[4] ; Stefania,Madonna ^[1] ; Cristina Maria,Failla ^[1] ; Cristina,Albanesi ^[1]

作者单位： Experimental Immunology Laboratory, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy. ^[1] Department of Dermatology, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy. ^[2] Department of Oncology, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy. ^[3] Anatomical Pathology Unit, Istituto Dermopatico dell'Immacolata (IDI-IRCCS), Rome, Italy. ^[4]

关键词 adaptive immunity anti-PD-1 therapy immune-related cutaneous adverse event (ircAE)innate immunity melanoma paradoxical skin reactions psoriasis

医学主题词人类(Humans);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);银屑病(Psoriasis);皮肤(Skin);肿瘤坏死因子α(Tumor Necrosis Factor-alpha);氨肽酶类(Aminopeptidases);次要组织相容性抗原(Minor Histocompatibility Antigens)

DOI 10.3389/fimmu.2024.1346687

PMID 38495872

发布时间 2024-11-02

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