miRNA-27a-3p is involved in the plasticity of differentiated hepatocytes.

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作者： Debora,Salerno ^[1] ; Giovanna,Peruzzi ^[2] ; Giuseppe Rubens Pascucci ^[3] ; Massimo,Levrero ^[4] ; Laura,Belloni ^[5] ; Natalia,Pediconi ^[6]

作者单位： Dept. of Molecular Medicine, Sapienza University of Rome, Italy; Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy. ^[1] Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy. ^[2] Research Unit of Clinical Immunology and Vaccinology, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Department of Systems Medicine, University of Rome "Tor Vergata", Italy. ^[3] Cancer Research Center of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Lyon, France. ^[4] Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Dept. of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Via Giorgio Nicola Papanicolau, 00189 Rome, Italy. Electronic address: laura.belloni@uniroma1.it. ^[5] Center for Life Nano & Neuro Science, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Rome, Italy; Dept. of Experimental Medicine, Sapienza University of Rome, Viale Regina Elena 324, 00161 Rome, Italy. Electronic address: natalia.pediconi@uniroma1.it. ^[6]

关键词 Differentiated HepaRG cells (dHepaRG)Epigenetic GSK-J4 Liver plasticity hsa-miR-27a-3p miRNA-Seq

主题词人类(Humans);肝细胞(Hepatocytes);微RNAs(MicroRNAs);肝(Liver);细胞分化(Cell Differentiation);后成说, 遗传(Epigenesis, Genetic)

DOI 10.1016/j.gene.2024.148387

PMID 38499211

发布时间 2024-04-22

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