Dictyophora indusiata polysaccharide mediates priming of the NLRP3 inflammasome activation via TLR4/ NF-κB signaling pathway to exert immunostimulatory effects.

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第一作者： Youyi,Liu

第一单位： Jiangnan University, Wuxi School of Medicine, Wuxi, Jiangsu 214122, P.R. China.

作者： Youyi,Liu ^[1] ; Huanxiao,Zhang ^[1] ; Yuxuan,Li ^[1] ; Hanqian,Zha ^[1] ; Yujie,Gao ^[1] ; Hui,Chen ^[2] ; Yalin,Wang ^[1] ; Tongxin,Zhou ^[2] ; Chao,Deng ^[1]

作者单位： Jiangnan University, Wuxi School of Medicine, Wuxi, Jiangsu 214122, P.R. China. ^[1] Yixing Hospital of Traditional Chinese Medicine, Wuxi, Jiangsu 214200, P.R. China. ^[2]

关键词 Dictyophora indusiata polysaccharide Immunostimulatory activity Macrophage NLRP3 inflammasome

主题词 NF-κB(NF-kappa B);炎性体(Inflammasomes);Toll样受体4(Toll-Like Receptor 4);信号传导(Signal Transduction);多糖类(Polysaccharides);担子菌纲(Basidiomycota)

DOI 10.32725/jab.2024.005

PMID 38505967

发布时间 2024-03-21

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