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ENPP2/Autotaxin: The potential drug target for alcoholic liver disease identified through Mendelian randomization analysis.

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第一作者： Peiqiong,Luo

第一单位： Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.;Branch of National Clinical Research Center for Metabolic Diseases, Wuhan, Hubei, China.

作者： Peiqiong,Luo ^[1] ; Xuefeng,Yu ^[1]

作者单位： Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.;Branch of National Clinical Research Center for Metabolic Diseases, Wuhan, Hubei, China. ^[1]

关键词 Bayesian colocalization analysis ENPP2/Autotaxin Mendelian randomization analysis alcoholic liver disease drug targets mediation analysis

医学主题词孟德尔随机化分析(Mendelian Randomization Analysis);肝疾病, 酒精性(Liver Diseases, Alcoholic);基因表达调控(Gene Expression Regulation);磷酸二酯水解酶类(Phosphoric Diester Hydrolases);人类(Humans);计算生物学(Computational Biology);危险因素(Risk Factors)

DOI 10.1111/liv.15905

PMID 38517150

发布时间 2026-04-14

基金项目

82270880, 81974109/National Natural Science Foundation of China

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