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Phasing Diploid Genome Assembly Graphs with Single-Cell Strand Sequencing.

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第一作者： Mir,Henglin

第一单位： Institute for Medical Biometry and Bioinformatics, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Germany.;Center for Digital Medicine, Heinrich Heine University Düsseldorf, Germany.

作者： Mir,Henglin ^[1] ; Maryam,Ghareghani ^[2] ; William,Harvey ^[3] ; David,Porubsky ^[3] ; Sergey,Koren ^[4] ; Evan E,Eichler ^[5] ; Peter,Ebert ^[6] ; Tobias,Marschall ^[1]

作者单位： Institute for Medical Biometry and Bioinformatics, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Germany.;Center for Digital Medicine, Heinrich Heine University Düsseldorf, Germany. ^[1] Department of Mathematics and Computer Science, Freie Universität Berlin, Germany.;Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Berlin, Germany. ^[2] Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA. ^[3] Genome Informatics Section, Computational and Statistical Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. ^[4] Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA, USA.;Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. ^[5] Core Unit Bioinformatics, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Germany.;Institute for Medical Biometry and Bioinformatics, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Germany.;Center for Digital Medicine, Heinrich Heine University Düsseldorf, Germany. ^[6]

关键词 Assembly Graph Haplotype Hi-C Phasing Strand-seq Trio Verkko de-novo Assembly hifiasm

DOI 10.1101/2024.02.15.580432

PMID 38529499

发布时间 2024-10-23

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