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Greater white matter degeneration and lower structural connectivity in non-amnestic vs. amnestic Alzheimer's disease.

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第一作者： Jeffrey S,Phillips

第一单位： Penn Frontotemporal Degeneration Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.;Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

作者： Jeffrey S,Phillips ^[1] ; Nagesh,Adluru ^[2] ; Moo K,Chung ^[3] ; Hamsanandini,Radhakrishnan ^[1] ; Christopher A,Olm ^[1] ; Philip A,Cook ^[4] ; James C,Gee ^[4] ; Katheryn A Q,Cousins ^[1] ; Sanaz,Arezoumandan ^[5] ; David A,Wolk ^[6] ; Corey T,McMillan ^[1] ; Murray,Grossman ^[1] ; David J,Irwin ^[1]

作者单位： Penn Frontotemporal Degeneration Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.;Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. ^[1] Waisman Center, University of Wisconsin-Madison, Madison, WI, United States.;Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States. ^[2] Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States. ^[3] Penn Image Computing and Science Laboratory, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. ^[4] Penn Frontotemporal Degeneration Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States. ^[5] Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.;Penn Memory Center, University of Pennsylvania Health System, Philadelphia, PA, United States. ^[6]

关键词 behavioral variant Alzheimer’s disease corticobasal syndrome (CBS)diffusion MRI (dMRI)logopenic variant of primary progressive aphasia (lvPPA)network topology analysis non-amnestic Alzheimer’s disease posterior cortical atrophy (PCA)

DOI 10.3389/fnins.2024.1353306

PMID 38567286

发布时间 2025-07-21

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