Inhibition of TREM-1 alleviates neuroinflammation by modulating microglial polarization via SYK/p38MAPK signaling pathway after traumatic brain injury.

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作者： Tianqi,Zhao ^[1] ; Yuxin,Zhou ^[1] ; Dabing,Zhang ^[1] ; Dong,Han ^[2] ; Jingyuan,Ma ^[1] ; Shanshan,Li ^[1] ; Ting,Li ^[3] ; Shuqun,Hu ^[4] ; Zhouru,Li ^[5]

作者单位： Department of Forensic Science, Xuzhou Medical University, Xuzhou, Jiangsu, China; Jiangsu Medical Engineering Research Center of Gene Detection, Xuzhou, Jiangsu, China. ^[1] Laboratory of Emergency Medicine, Second Clinical Medical College of Xuzhou Medical University, Xuzhou, Jiangsu, China; Xuzhou Key Laboratory of Emergency Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China. ^[2] Jiangsu Medical Engineering Research Center of Gene Detection, Xuzhou, Jiangsu, China; School of Life Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, China. Electronic address: tingli8@xzhmu.edu.cn. ^[3] Laboratory of Emergency Medicine, Second Clinical Medical College of Xuzhou Medical University, Xuzhou, Jiangsu, China; Xuzhou Key Laboratory of Emergency Medicine, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China. Electronic address: hushuqun88@xzhmu.edu.cn. ^[4] Department of Forensic Science, Xuzhou Medical University, Xuzhou, Jiangsu, China; Jiangsu Medical Engineering Research Center of Gene Detection, Xuzhou, Jiangsu, China. Electronic address: lzhr@xzhmu.edu.cn. ^[5]

关键词 Microglia Neuroinflammation TREM-1 Traumatic brain injury (TBI)p38MAPK