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首页> Nature communications> Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice.

Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome and intestinal immune homeostasis in mice.

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作者： Tatsuya,Dokoshi ^[1] ; Yang,Chen ^[1] ; Kellen J,Cavagnero ^[2] ; Gibraan,Rahman ^[1] ; Daniel,Hakim ^[2] ; Samantha,Brinton ^[2] ; Hana,Schwarz ^[1] ; Elizabeth A,Brown ^[1] ; Alan,O'Neill ^[1] ; Yoshiyuki,Nakamura ^[1] ; Fengwu,Li ^[1] ; Nita H,Salzman ^[1] ; Rob,Knight ^[3] ; Richard L,Gallo ^[2]

作者单位： Department of Dermatology, University of California, San Diego, La Jolla, CA, USA. ^[1] Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA. ^[2] Department of Pediatrics, Division of Gastroenterology and Center for Microbiome Research, Medical College of Wisconsin, Milwaukee, WI, USA. ^[3] Department of Computer Science & Engineering, University of California, San Diego, La Jolla, CA, USA. ^[4] Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA. ^[5] Center for Microbiome Innovation, University of California, San Diego, La Jolla, CA, USA. ^[6] Department of Dermatology, University of California, San Diego, La Jolla, CA, USA. rgallo@ucsd.edu. ^[7]

主题词小鼠(Mice);动物(Animals);透明质酸(Hyaluronic Acid);结肠炎(Colitis);肠黏膜(Intestinal Mucosa);硫酸葡聚糖(Dextran Sulfate);小鼠, 近交C57BL(Mice, Inbred C57BL);疾病模型, 动物(Disease Models, Animal);结肠(Colon)

DOI 10.1038/s41467-024-47072-3

PMID 38589392

发布时间 2024-04-11

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Nature communications

Nature communications

2024年15卷1期

3009页

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