CDK4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma.

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第一作者： Ke,Cheng

第一单位： Division of Pancreatic Surgery, Department of General Surgery, West China Hospital of Sichuan University, Chengdu, China.

作者： Ke,Cheng ^[1] ; Zijian,Zhou ^[1] ; Qiangxing,Chen ^[1] ; Zixin,Chen ^[1] ; Yu,Cai ^[1] ; He,Cai ^[1] ; Shangdi,Wu ^[1] ; Pan,Gao ^[1] ; Yunqiang,Cai ^[1] ; Jin,Zhou ^[2] ; Xin,Wang ^[1] ; Zhong,Wu ^[3] ; Bing,Peng ^[4]

作者单位： Division of Pancreatic Surgery, Department of General Surgery, West China Hospital of Sichuan University, Chengdu, China. ^[1] Division of Liver Surgery, Department of General Surgery, West China Hospital of Sichuan University, Chengdu, China. ^[2] Division of Pancreatic Surgery, Department of General Surgery, West China Hospital of Sichuan University, Chengdu, China. wuzhong057@scu.edu.cn. ^[3] Division of Pancreatic Surgery, Department of General Surgery, West China Hospital of Sichuan University, Chengdu, China. drpengbing123@163.com. ^[4]

关键词 Drug resistance PDAC Palbociclib Trametinib

DOI 10.1038/s41598-024-57417-z

PMID 38600093

发布时间 2024-04-10

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Scientific reports

2024年14卷1期

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CDK4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma.

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CDK4/6 inhibition sensitizes MEK inhibition by inhibiting cell cycle and proliferation in pancreatic ductal adenocarcinoma.

Scientific reports

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