Ursodeoxycholic acid loaded dual-modified graphene oxide nanocomposite alleviates cholestatic liver injury through inhibiting hepatocyte apoptosis.

导出 LinkOut

翻译打印收藏纠错

第一作者： Wanyi,Zhou

第一单位： Department of Urology, Institute of Surgery Research, Army Medical Center, Daping Hospital, Army Medical University, Chongqing 400042, China.

作者： Wanyi,Zhou ^[1] ; Xinrui,Yang ^[2] ; Yaru,Yin ^[2] ; Si,Chen ^[3] ; Luxun,Yang ^[2] ; Tao,Li ^[2] ; Jing,Liu ^[2] ; Binghui,Lu ^[2] ; Zhangyou,Yang ^[4] ; Rong,Li ^[5] ; Mingman,Zhang ^[6]

作者单位： Department of Urology, Institute of Surgery Research, Army Medical Center, Daping Hospital, Army Medical University, Chongqing 400042, China. ^[1] State Key Laboratory of Trauma and Chemical Poisoning, Military Key Laboratory of Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing 400038, China. ^[2] Department of Pediatric Hepatobiliary Surgery, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400015, China. ^[3] Chongqing Key Laboratory for Pharmaceutical Metabolism Research, Chongqing Pharmacodynamic Evaluation Engineering Technology Research Center, College of Pharmacy, Chongqing Medical University, Chongqing 400016, China. ^[4] State Key Laboratory of Trauma and Chemical Poisoning, Military Key Laboratory of Nanomedicine, College of Preventive Medicine, Army Medical University, Chongqing 400038, China. Electronic address: lrong361@126.com. ^[5] Department of Pediatric Hepatobiliary Surgery, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400015, China. Electronic address: zhangmingman_a@163.com. ^[6]

关键词 Apoptosis Autophagy Cholestatic liver injury Graphene oxide Ursodeoxycholic acid