Assessment of the <i>Artemia salina</i> toxicity assay as a substitute of the mouse lethality assay in the determination of venom-induced toxicity and preclinical efficacy of antivenom.

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第一作者： Xavier,Araya

第一单位： Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.

作者： Xavier,Araya ^[1] ; Mitchel,Okumu ^[2] ; Gina,Durán ^[1] ; Aarón,Gómez ^[1] ; José María,Gutiérrez ^[1] ; Guillermo,León ^[1]

作者单位： Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica. ^[1] Department of Public Health, Pharmacology and Toxicology, University of Nairobi, Kenya. ^[2]

关键词 Antivenom Artemia salina toxicity test Neutralization of lethality Preclinical efficacy Snake venom

DOI 10.1016/j.toxcx.2024.100195

PMID 38606385

发布时间 2024-04-25

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2024年22卷

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Assessment of the <i>Artemia salina</i> toxicity assay as a substitute of the mouse lethality assay in the determination of venom-induced toxicity and preclinical efficacy of antivenom.

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Assessment of the <i>Artemia salina</i> toxicity assay as a substitute of the mouse lethality assay in the determination of venom-induced toxicity and preclinical efficacy of antivenom.

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