Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol.

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第一作者： Shijiang,Huang

第一单位： State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China.

作者： Shijiang,Huang ^[1] ; Yuanjun,Jiang ^[1] ; Jing,Li ^[2] ; Linlin,Mao ^[1] ; Zeyou,Qiu ^[3] ; Sheng,Zhang ^[1] ; Yuhui,Jiang ^[1] ; Yong,Liu ^[1] ; Wen,Liu ^[1] ; Zhi,Xiong ^[1] ; Wuju,Zhang ^[4] ; Xiaolin,Liu ^[1] ; Yue,Zhang ^[1] ; Xiaochun,Bai ^[5] ; Bin,Guo ^[6]

作者单位： State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China. ^[1] Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China. ^[2] Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China.;Equipment Material Department, West China Xiamen Hospital of Sichuan University, Xiamen, Fujian, 361000, China. ^[3] State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China.;Central Laboratory, The Fifth Affiliated Hospital, Southern Medical University, Guangzhou, Guangdong, 510900, China. ^[4] State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China.;Guangdong Provincial Key Laboratory of Bone and Joint Degenerative Diseases, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, 510630, China. ^[5] State Key Laboratory of Organ Failure Research, Department of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China.;The Tenth Affiliated Hospital, Southern Medical University, Dongguan, Guangdong, 523018, China. ^[6]

关键词 CYP7A1 SAA3 bone‐liver crosstalk hypercholesterolaemia osteocytes/osteoblasts

主题词动物(Animals);血清淀粉样蛋白A(Serum Amyloid A Protein);小鼠(Mice);胆固醇(Cholesterol);肝(Liver);骨细胞(Osteocytes);成骨细胞(Osteoblasts);高胆固醇血症(Hypercholesterolemia);疾病模型, 动物(Disease Models, Animal);胆固醇7-α-羟化酶(Cholesterol 7-alpha-Hydroxylase);男(雄)性(Male)

DOI 10.1002/advs.202307818

PMID 38613835

发布时间 2024-07-22

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

2024年11卷24期

e2307818页

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Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Osteocytes/Osteoblasts Produce SAA3 to Regulate Hepatic Metabolism of Cholesterol.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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Advanced science (Weinheim, Baden-Wurttemberg, Germany)

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