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A new test for trait mean and variance detects unreported loci for blood-pressure variation.

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作者单位: Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Biostatistics and Computational Biology Branch, Division of Intramural Research, National Institute of Environmental Health Sciences, Durham, NC, USA. [1] Population Analytics and Insights, Data Sciences, Janssen Research and Development, Spring House, PA, USA. [2] Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA. [3] Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. [4] Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA. [5] Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA. [6] Department of Maternal and Fetal Medicine, Orlando Health, Orlando, FL, USA; Genetic Counseling Program, Bay Path University, Longmeadow, MA, USA. [7] Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA. [8] Center of Clinical Pharmacology and Precision Medicine, Queen Mary University, London, England. [9] Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Division of Quantitative Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, TN, USA. [10] Department of Epidemiology and Biostatistics, Institute for Computational Biology, Case Western Reserve University, Cleveland, OH, USA. [11] Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA. [12] Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: todd.l.edwards@vumc.org. [13]
DOI 10.1016/j.ajhg.2024.03.014
PMID 38614075
发布时间 2024-11-03
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American journal of human genetics

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