换一批
换一批Spatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis.
作者：
Masahiro,Hashimoto [1]
;
Yasuhiro,Kojima [2]
;
Takeharu,Sakamoto [3]
;
Yuki,Ozato [1]
;
Yusuke,Nakano [1]
;
Tadashi,Abe [4]
;
Kiyotaka,Hosoda [4]
;
Hideyuki,Saito [5]
;
Satoshi,Higuchi [1]
;
Yuichi,Hisamatsu [4]
;
Takeo,Toshima [4]
;
Yusuke,Yonemura [4]
;
Takaaki,Masuda [4]
;
Tsuyoshi,Hata [6]
;
Satoshi,Nagayama [7]
;
Koichi,Kagawa [8]
;
Yasuhiro,Goto [8]
;
Mitsuaki,Utou [9]
;
Ayako,Gamachi [10]
;
Kiyomi,Imamura [11]
;
Yuta,Kuze [11]
;
Junko,Zenkoh [11]
;
Ayako,Suzuki [11]
;
Kazuki,Takahashi [12]
;
Atsushi,Niida [12]
;
Haruka,Hirose [13]
;
Shuto,Hayashi [13]
;
Jun,Koseki [13]
;
Satoshi,Fukuchi [14]
;
Kazunari,Murakami [15]
;
Tomoharu,Yoshizumi [16]
;
Kenji,Kadomatsu [17]
;
Taro,Tobo [9]
;
Yoshinao,Oda [18]
;
Mamoru,Uemura [6]
;
Hidetoshi,Eguchi [6]
;
Yuichiro,Doki [6]
;
Masaki,Mori [19]
;
Masanobu,Oshima [20]
;
Tatsuhiro,Shibata [12]
;
Yutaka,Suzuki [11]
;
Teppei,Shimamura [21]
;
Koshi,Mimori [22]
作者单位：
Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan; Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.
[1]
Division of Computational Bioscience, National Cancer Center Research Institute, Tokyo, 104-0045, Japan.
[2]
Department of Cancer Biology, Institute of Biomedical Science, Kansai Medical University, Hirakata, 573-1010, Japan. Electronic address: sakamott@hirakata.kmu.ac.jp.
[3]
Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan.
[4]
Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan; Department of General Surgical Science, Gastroenterological Surgery, Gunma University Graduate School of Medicine, Maebashi, 371-8511, Japan.
[5]
Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, Suita, 565-0871, Japan.
[6]
Department of Surgery, Uji-Tokushukai Medical Center, Uji, 611-0041, Japan.
[7]
Department of Gastroenterology, Shin Beppu Hospital, Beppu, 874-8538, Japan.
[8]
Department of Pathology, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan.
[9]
Department of Pathology, Oita Oka Hospital, Oita, 870-0192, Japan.
[10]
Laboratory of Systems Genomics, Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, 277-8561, Japan.
[11]
Laboratory of Molecular Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, 108-8639, Japan.
[12]
Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
[13]
Department of Gastroenterological Medicine, Almeida Memorial Hospital, Oita, 870-1195, Japan.
[14]
Department of Gastroenterology, Oita University Hospital, Yufu, 879-5593, Japan.
[15]
Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.
[16]
Department of Biochemistry, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan.
[17]
Department of Anatomic Pathology, Kyushu University Hospital, Fukuoka, 812-8582, Japan.
[18]
Tokai University School of Medicine, Isehara, 259-1193, Japan.
[19]
Division of Genetics, Cancer Research Institute, Kanazawa University, Kanazawa, 920-1192, Japan.
[20]
Division of Systems Biology, Nagoya University Graduate School of Medicine, Nagoya, 466-8550, Japan; Department of Computational and Systems Biology, Medical Research Insitute, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo 113-0034, Japan. Electronic address: shimamura@med.nagoya-u.ac.jp.
[21]
Department of Surgery, Kyushu University Beppu Hospital, Beppu, 874-0838, Japan. Electronic address: mimori.koshi.791@m.kyushu-u.ac.jp.
[22]
主题词
女(雌)性(Female);人类(Humans);男(雄)性(Male);细胞间通讯(Cell Communication);结直肠肿瘤(Colorectal Neoplasms);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);免疫耐受(Immune Tolerance);单细胞分析(Single-Cell Analysis);T淋巴细胞, 调节性(T-Lymphocytes, Regulatory);肿瘤微环境(Tumor Microenvironment)
DOI
10.1016/j.ebiom.2024.105102
PMID
38614865
发布时间
2024-08-07
- 浏览0
EBioMedicine
2024年103卷
105102页
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