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Phase-amplitude coupling detection and analysis of human 2-dimensional neural cultures in multi-well microelectrode array in vitro.

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第一作者： Yousef,Salimpour

第一单位： Functional Neurosurgery Laboratory, Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

作者： Yousef,Salimpour ^[1] ; William S,Anderson ^[1] ; Raha,Dastgheyb ^[2] ; Shiyu,Liu ^[2] ; Guo-Li,Ming ^[3] ; Hongjun,Song ^[3] ; Nicholas J,Maragakis ^[2] ; Christa W,Habela ^[4]

作者单位： Functional Neurosurgery Laboratory, Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA. ^[1] Department of Neurology, Johns Hopkins School of Medicine, Baltimore MD, USA. ^[2] 1Department of Neuroscience and Mahoney Institute for Neurosciences, Perelman School of Medicine, Philadelphia, PA, USA. ^[3] Department of Neurology, Johns Hopkins School of Medicine, Baltimore MD, USA. Electronic address: chabela1@jh.edu. ^[4]

关键词 Cross-frequency coupling Multielectrode array Parkinson's disease Phase-amplitude coupling epilepsy human astrocyte human neuronal culture induced pluripotent stem cells (iPSC)

医学主题词人类(Humans);微电极(Microelectrodes);神经元(Neurons);诱导多能干细胞(Induced Pluripotent Stem Cells);动作电位(Action Potentials);细胞, 培养的(Cells, Cultured);大脑皮质(Cerebral Cortex);星形细胞(Astrocytes);细胞培养技术(Cell Culture Techniques);荷包牡丹碱(Bicuculline);神经网(Nerve Net)

DOI 10.1016/j.jneumeth.2024.110127

PMID 38615721

发布时间 2025-03-04

基金项目

R35 NS097370/NS/NINDS NIH HHS/United States K12 NS098482/NS/NINDS NIH HHS/United States R01 NS117604/NS/NINDS NIH HHS/United States K08 NS102526/NS/NINDS NIH HHS/United States R35 NS116843/NS/NINDS NIH HHS/United States

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