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APOBEC shapes tumor evolution and age at onset of lung cancer in smokers.

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第一作者： Tongwu,Zhang

第一单位： Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.

作者： Tongwu,Zhang ^[1] ; Jian,Sang ^[1] ; Phuc H,Hoang ^[1] ; Wei,Zhao ^[1] ; Jennifer,Rosenbaum ^[2] ; Kofi Ennu,Johnson ^[3] ; Leszek J,Klimczak ^[4] ; John,McElderry ^[1] ; Alyssa,Klein ^[1] ; Christopher,Wirth ^[5] ; Erik N,Bergstrom ^[6] ; Marcos,Díaz-Gay ^[6] ; Raviteja,Vangara ^[6] ; Frank,Colon-Matos ^[1] ; Amy,Hutchinson ^[7] ; Scott M,Lawrence ^[7] ; Nathan,Cole ^[7] ; Bin,Zhu ^[1] ; Teresa M,Przytycka ^[8] ; Jianxin,Shi ^[1] ; Neil E,Caporaso ^[1] ; Robert,Homer ^[9] ; Angela C,Pesatori ^[10] ; Dario,Consonni ^[11] ; Marcin,Imielinski ^[3] ; Stephen J,Chanock ^[1] ; David C,Wedge ^[5] ; Dmitry A,Gordenin ^[12] ; Ludmil B,Alexandrov ^[6] ; Reuben S,Harris ^[13] ; Maria Teresa,Landi ^[1]

作者单位： Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA. ^[1] Westat, Rockville, MD, USA. ^[2] New York Genome Center, New York, USA. ^[3] Integrative Bioinformatics Support Group, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. ^[4] Manchester Cancer Research Centre, The University of Manchester, Manchester, UK. ^[5] Department of Cellular and Molecular Medicine and Department of Bioengineering and Moores Cancer Center, University of California San Diego, La Jolla, CA, USA. ^[6] Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA.;Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research, Frederick, MD, USA. ^[7] National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA. ^[8] Department of Pathology, Yale School of Medicine, New Haven, CT, USA. ^[9] Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.;Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. ^[10] Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. ^[11] Genome Integrity and Structural Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. ^[12] Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, TX, USA.;Howard Hughes Medical Institute, University of Texas Health San Antonio, San Antonio, TX, USA. ^[13]

DOI 10.1101/2024.04.02.587805

PMID 38617360

发布时间 2025-07-19

基金项目

P50 CA247749/CA/NCI NIH HHS/United States R01 CA269919/CA/NCI NIH HHS/United States ZIA CP101231/ImNIH/Intramural NIH HHS/United States P01 CA234228/CA/NCI NIH HHS/United States R01 ES030993/ES/NIEHS NIH HHS/United States R01 ES032547/ES/NIEHS NIH HHS/United States

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