Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK signaling and cell cycle progression.

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作者： Kentaro,Watanabe ^[1] ; Keiji,Tasaka ^[2] ; Hideto,Ogata ^[2] ; Shota,Kato ^[1] ; Hiroo,Ueno ^[3] ; Katsutsugu,Umeda ^[2] ; Tomoya,Isobe ^[1] ; Yasuo,Kubota ^[1] ; Masahiro,Sekiguchi ^[1] ; Shunsuke,Kimura ^[4] ; Aiko,Sato-Otsubo ^[1] ; Mitsuteru,Hiwatari ^[5] ; Tetsuo,Ushiku ^[6] ; Motohiro,Kato ^[1] ; Akira,Oka ^[1] ; Satoru,Miyano ^[7] ; Seishi,Ogawa ^[8] ; Junko,Takita ^[9]

作者单位： Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ^[1] Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[2] Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.;Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. ^[3] Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.;Department of Pediatrics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. ^[4] Department of Pediatrics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.;Department of Pediatrics, Teikyo University, School of Medicine, Tokyo, Japan. ^[5] Department of Pathology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. ^[6] Department of Integrated Analytics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan. ^[7] Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.;Department of Pathology and Tumor Biology, Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan. ^[8] Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan. jtakita@kuhp.kyoto-u.ac.jp. ^[9]