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Ketamine induces multiple individually distinct whole-brain functional connectivity signatures.

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第一作者： Flora,Moujaes

第一单位： Department of Psychiatry, Yale University School of Medicine, New Haven, United States.;Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital for Psychiatry Zurich, Zurich, Switzerland.

作者： Flora,Moujaes ^[1] ; Jie Lisa,Ji ^[2] ; Masih,Rahmati ^[2] ; Joshua B,Burt ^[3] ; Charles,Schleifer ^[4] ; Brendan D,Adkinson ^[5] ; Aleksandar,Savic ^[6] ; Nicole,Santamauro ^[2] ; Zailyn,Tamayo ^[2] ; Caroline,Diehl ^[7] ; Antonija,Kolobaric ^[8] ; Morgan,Flynn ^[9] ; Nathalie,Rieser ^[10] ; Clara,Fonteneau ^[2] ; Terry,Camarro ^[11] ; Junqian,Xu ^[12] ; Youngsun,Cho ^[13] ; Grega,Repovs ^[14] ; Sarah K,Fineberg ^[2] ; Peter T,Morgan ^[15] ; Erich,Seifritz ^[10] ; Franz X,Vollenweider ^[10] ; John H,Krystal ^[2] ; John D,Murray ^[16] ; Katrin H,Preller ^[1] ; Alan,Anticevic ^[17]

作者单位： Department of Psychiatry, Yale University School of Medicine, New Haven, United States.;Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital for Psychiatry Zurich, Zurich, Switzerland. ^[1] Department of Psychiatry, Yale University School of Medicine, New Haven, United States. ^[2] Department of Physics, Yale University, Boston, United States. ^[3] David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, United States. ^[4] Interdepartmental Neuroscience Program, Yale University, New Haven, United States. ^[5] Department of Psychiatry, University of Zagreb, Zagreb, Croatia. ^[6] Department of Psychology, University of California, Los Angeles, Los Angeles, United States. ^[7] Center of Neuroscience, University of Pittsburgh, Pittsburgh, United States. ^[8] Department of Psychiatry, Vanderbilt University Medical Center, Nashville, United States. ^[9] Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital for Psychiatry Zurich, Zurich, Switzerland. ^[10] Magnetic Resonance Research Center, Yale University School of Medicine, New Haven, United States. ^[11] Department of Radiology and Psychiatry, Baylor College of Medicine, Houston, United States. ^[12] Department of Psychiatry, Yale University School of Medicine, New Haven, United States.;Child Study Center, Yale University School of Medicine, New Haven, United States. ^[13] Department of Psychology, University of Ljubljana, Ljubljana, Slovenia. ^[14] Department of Psychiatry, Yale University School of Medicine, New Haven, United States.;Department of Psychiatry, Bridgeport Hospital, Bridgeport, United States. ^[15] Department of Psychiatry, Yale University School of Medicine, New Haven, United States.;Department of Physics, Yale University, Boston, United States.;Department of Psychology, Yale University, New Haven, United States. ^[16] Department of Psychiatry, Yale University School of Medicine, New Haven, United States.;Interdepartmental Neuroscience Program, Yale University, New Haven, United States. ^[17]

关键词 data reduction fMRI gene expression human inter-individual variation ketamine medicine neuroscience

医学主题词人类(Humans);氯胺酮(Ketamine);单盲法(Single-Blind Method);抗抑郁药(Antidepressive Agents);脑(Brain)

DOI 10.7554/eLife.84173

PMID 38629811

发布时间 2026-03-07

基金项目

DP5OD012109-01/NH/NIH HHS/United States U01 MH121766/MH/NIMH NIH HHS/United States 1U01MH121766/NH/NIH HHS/United States R01 MH112746/MH/NIMH NIH HHS/United States P50 AA012870/AA/NIAAA NIH HHS/United States R01 MH108590/MH/NIMH NIH HHS/United States 5R01MH112189/NH/NIH HHS/United States 5R01MH108590/NH/NIH HHS/United States R01MH112746/NH/NIH HHS/United States DP5 OD012109/OD/NIH HHS/United States R01 MH112189/MH/NIMH NIH HHS/United States 2P50AA012870-11/AA/NIAAA NIH HHS/United States

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