14-3-3τ as a Modulator of Early α-Synuclein Multimerization and Amyloid Formation.

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作者： Gobert,Heesink ^[1] ; Maxime C M,van den Oetelaar ^[2] ; Slav A,Semerdzhiev ^[1] ; Christian,Ottmann ^[2] ; Luc,Brunsveld ^[2] ; Christian,Blum ^[1] ; Mireille M A E,Claessens ^[1]

作者单位： Nanobiophysics, Faculty of Science and Technology, MESA + Institute for Nanotechnology and Technical Medical Centre, University of Twente, Enschede 7500 AE, The Netherlands. ^[1] Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven 5600 MB, The Netherlands. ^[2]

关键词 14-3-3 chaperone IDP multimerization modulation of multimerization protein co-condensation protein-protein interactions α-synuclein aggregation

主题词 α突触核蛋白(alpha-Synuclein);14-3-3蛋白质类(14-3-3 Proteins);人类(Humans);淀粉样蛋白(Amyloid);蛋白质多聚化(Protein Multimerization);帕金森病(Parkinson Disease)

DOI 10.1021/acschemneuro.4c00100

PMID 38635928

发布时间 2024-06-13

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