GATA4 regulates the transcription of MMP9 to suppress the invasion and migration of breast cancer cells via HDAC1-mediated p65 deacetylation.
第一作者:
Yuxi,Yang
第一单位:
School of Bioengineering & Key Laboratory of Protein Modification and Disease, Liaoning Province, Dalian University of Technology, Dalian, 116024, China.
作者:
主题词
人类(Humans);GATA4转录因子(GATA4 Transcription Factor);乳腺肿瘤(Breast Neoplasms);基质金属蛋白酶9(Matrix Metalloproteinase 9);女(雌)性(Female);细胞运动(Cell Movement);组蛋白脱乙酰基酶1(Histone Deacetylase 1);动物(Animals);肿瘤侵润(Neoplasm Invasiveness);乙酰化作用(Acetylation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);细胞系, 肿瘤(Cell Line, Tumor);小鼠(Mice);转录因子RelA(Transcription Factor RelA);转录, 遗传(Transcription, Genetic);启动区, 遗传(Promoter Regions, Genetic);小鼠, 裸(Mice, Nude);小鼠, 近交BALB C(Mice, Inbred BALB C)
DOI
10.1038/s41419-024-06656-z
PMID
38653973
发布时间
2025-01-14
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