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A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.

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第一作者: Hannah,Baumeister
第一单位: German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.
作者单位: German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany. [1] Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden. [2] Department of Psychiatry and Behavioral Sciences, University of California, San Francisco, San Francisco, CA 94143, USA. [3] German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.;Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany. [4] Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany. [5] German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.;Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany. [6] German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.;Institute for Medical Biometry, University Hospital Bonn, 53127 Bonn, Germany. [7] German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany. [8] Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany. [9] German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.;Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany. [10] Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany. [11] Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075 Göttingen, Germany. [12] Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075 Göttingen, Germany.;German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.;Leibniz Institute for Neurobiology, 39118 Magdeburg, Germany. [13] Department of Psychiatry, Medical Faculty, University of Cologne, 50937 Cologne, Germany. [14] German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.;Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany.;Department of Psychiatry and Psychotherapy, Otto-von-Guericke University, 39120 Magdeburg, Germany. [15] Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-Universität, 81377 Munich, Germany. [16] Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität, 80336 Munich, Germany.;Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield S10 2HQ, UK.;Department of Neuroradiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany. [17] German Center for Neurodegenerative Diseases (DZNE), 18147 Rostock, Germany.;Department of Psychosomatic Medicine, Rostock University Medical Center, 18147 Rostock, Germany. [18] German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.;Department of Psychiatry and Psychotherapy, University of Tübingen, 72076 Tübingen, Germany. [19] Berlin Center for Advanced Neuroimaging, Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. [20] MR-Research in Neurosciences, Department of Cognitive Neurology, Georg-August-University Göttingen, 37075 Göttingen, Germany. [21] Institute for Stroke and Dementia Research (ISD), Ludwig-Maximilians-Universität, 81377 Munich, Germany.;German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany. [22] Department for Biomedical Magnetic Resonance, University of Tübingen, 72076 Tübingen, Germany. [23] Diagnostic Radiology, Institution of Clinical Sciences Lund, Lund University, 211 84 Lund, Sweden.;Image and Function, Skåne University Hospital, 211 84 Lund, Sweden. [24] Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.;Department of Neurology, Skåne University Hospital, Lund University, 211 84 Lund, Sweden.;Wallenberg Center for Molecular Medicine, Lund University, 22184 Lund, Sweden. [25] Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.;Memory Clinic, Skåne University Hospital, 205 02 Malmö, Sweden. [26] German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.;Department of Neurology, University of Bonn, 53127 Bonn, Germany. [27] German Center for Neurodegenerative Diseases (DZNE), 72076 Tübingen, Germany.;Department of Psychiatry and Psychotherapy, University of Tübingen, 72076 Tübingen, Germany.;Section for Dementia Research, Hertie Institute for Clinical Brain Research, 72076 Tübingen, Germany. [28] Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-Universität, 80336 Munich, Germany.;German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany.;Munich Cluster for Systems Neurology (SyNergy), 81377 Munich, Germany.;Ageing Epidemiology Research Unit (AGE), School of Public Health, Imperial College London, London SW7 2AZ, UK. [29] German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany.;Department of Psychiatry and Neurosciences, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 10117 Berlin, Germany.;Department of Psychiatry and Psychotherapy, Technical University of Munich, 81675 Munich, Germany.;Centre for Clinical Brain Sciences, University of Edinburgh and UK DRI, Edinburgh EH16 4SB, UK. [30] German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.;Department of Neurodegenerative Disease and Geriatric Psychiatry, University of Bonn Medical Center, 53127 Bonn, Germany.;Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany.;Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, University of Cologne, 50931 Cologne, Germany.;Department of Psychiatry & Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, The University of Texas at San Antonio, San Antonio, TX 78229, USA. [31] Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, 37075 Göttingen, Germany.;German Center for Neurodegenerative Diseases (DZNE), 37075 Göttingen, Germany.;Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal. [32] Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 4362, Belvaux, Luxembourg. [33] German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.;Institute of Cognitive Neurology and Dementia Research (IKND), Otto-von-Guericke University, 39120 Magdeburg, Germany.;Center for Behavioral Brain Sciences (CBBS), Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany. [34] German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany.;Department of Psychiatry, Medical Faculty, University of Cologne, 50937 Cologne, Germany.;Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany. [35] German Center for Neurodegenerative Diseases (DZNE), 39120 Magdeburg, Germany.;Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, 222 42 Lund, Sweden.;Center for Behavioral Brain Sciences (CBBS), Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany. [36]
DOI 10.1093/brain/awae118
PMID 38654513
发布时间 2024-07-07
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