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IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.

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第一作者： Radhika,Joshi

第一单位： Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, USA.

作者： Radhika,Joshi ^[1] ; Veronika,Brezani ^[1] ; Gabrielle M,Mey ^[2] ; Sergi,Guixé-Muntet ^[3] ; Marti,Ortega-Ribera ^[1] ; Yuan,Zhuang ^[1] ; Adam,Zivny ^[1] ; Sebastian,Werneburg ^[2] ; Jordi,Gracia-Sancho ^[4] ; Gyongyi,Szabo ^[1]

作者单位： Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, USA. ^[1] Department of Opthalmology and Visual Sciences, Kellogg Eye Center Michigan Neuroscience Institute, University of Michigan, Ann Arbor, USA.;Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA. ^[2] Liver Vascular Biology, IDIBAPS Biomedical Research Institute- CIBEREHD, Barcelona, Spain. ^[3] Liver Vascular Biology, IDIBAPS Biomedical Research Institute- CIBEREHD, Barcelona, Spain.;Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland. ^[4]

关键词 ARM Activated response microglia Alzheimer’s disease DAM IRF3 IRM Interferon response microglia Neuroinflammation Type 1 interferon ZBP1

DOI 10.1101/2024.03.08.582968

PMID 38654824

发布时间 2024-10-23

基金项目

R01 AA017729/AA/NIAAA NIH HHS/United States R01 AG072899/AG/NIA NIH HHS/United States

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IRF3 regulates neuroinflammatory responses and the expression of genes associated with Alzheimer's disease.

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