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Single-cell transcriptomics reveal distinct immune-infiltrating phenotypes and macrophage-tumor interaction axes among different lineages of pituitary neuroendocrine tumors.

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第一作者: Shaojian,Lin
第一单位: Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
作者: Shaojian,Lin [1] ; Yuting,Dai [2] ; Changxi,Han [3] ; Tianyi,Han [4] ; Linfeng,Zhao [1] ; Renyan,Wu [1] ; Jianyue,Liu [5] ; Bo,Zhang [6] ; Ning,Huang [5] ; Yanting,Liu [1] ; Shujing,Lai [3] ; Jintong,Shi [1] ; Yu,Wang [6] ; Meiqing,Lou [6] ; Jing,Xie [7] ; Yijun,Cheng [8] ; Hao,Tang [9] ; Hong,Yao [1] ; Hai,Fang [1] ; Yan,Zhang [1] ; Xuefeng,Wu [4] ; Lei,Shen [10] ; Youqiong,Ye [2] ; Li,Xue [11] ; Zhe Bao,Wu [12]
作者单位: Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [1] Department of Neurosurgery, Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [2] Department of Neurosurgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. [3] Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Rujin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [4] Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [5] Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [6] Department of Neurosurgery, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [7] Department of Neurosurgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [8] Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [9] Med-X Research Institute and School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China. [10] Shanghai Institute of Immunology, Department of Immunology and Microbiology and the Ministry of Education Key Laboratory of Cell Death and Differentiation, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [11] Department of Neurosurgery, Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lshen@shsmu.edu.cn. [12] Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lshen@shsmu.edu.cn. [13] Department of Neurosurgery, Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. youqiong.ye@shsmu.edu.cn. [14] Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China. youqiong.ye@shsmu.edu.cn. [15] Shanghai Institute of Immunology, Department of Immunology and Microbiology, State Key Laboratory of Systems Medicine for Cancer, Shanghai Jiao Tong University School of Medicine, Shanghai, China. youqiong.ye@shsmu.edu.cn. [16] Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. royxueli@126.com. [17] Department of Neurosurgery, Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. royxueli@126.com. [18] Shanghai Center for Brain Science and Brain-Inspired Technology, Shanghai, China. royxueli@126.com. [19] Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhebaowu@aliyun.com. [20] Department of Neurosurgery, Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhebaowu@aliyun.com. [21] Department of Neurosurgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. zhebaowu@aliyun.com. [22]
DOI 10.1186/s13073-024-01325-4
PMID 38658971
发布时间 2024-07-08
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